Insomnia

By Alice R. Laule, MD

When the famous seasonal poem says, ...and all through the house, not a creature was stirring, not even a mouse,” presumably that’s because they were all sound asleep. However, if you listen to the advertising on TV, you’d have to assume that in fact, probably several of the people in the house (perhaps not the mouse) had taken some sort of drug to achieve that sleep. Statistics say that one out of three people in the United States has some form of insomnia, either occasional or chronic. Sleep deprivation can really rob a person of their quality of life. Therefore this is an important issue, and one that I would bet a few of our Friends find themselves grappling with, at least from time to time.

            My own personal history of insomnia gives me some insight, although certainly not all the answers. My first bout of insomnia began in the late 80’s or early 90’s, and consisted of an absolute inability to fall asleep before 1 AM, no matter when I went to bed. I went to my first American Holistic Medical Association meeting in 1991, and because it simply was not readily available, did not drink my morning mug of coffee. I slept like a baby! At one of the lectures at that meeting, I learned that as we age our metabolism slows down and it can take more than 16 hours to metabolize caffeine. It was evidently remaining in my system until 1 AM. Ordinarily caffeine stays in the system for 6-8 hours, so my 9 AM mug of coffee should have been gone.

            I hear many, many patients tell me that they can drink coffee all day, even have a cup right before bed, and sleep just fine. However, be informed, sleep studies show that without exception the quality of sleep is poor, less restful than it could be, while coffee is still in the system. Alcohol also causes poor quality of sleep, though I know some people feel that the nightcap before they go to bed helps them get to sleep. The problem with alcohol is an abnormal wakefulness a few hours after the alcohol wears off.

            Insomnia can be divided into two general types, delayed onset of sleep, and poor maintenance of sleep. Things that work for one form of sleep problem don’t always work for the other form. Age also plays a role. Teenagers tend to run on a longer than 24 hour cycle as do people that have been put in environments where they have no contact with the outdoors. People have been put into caves, for instance, with only artificial lighting, and allowed to establish their own cyclic routines. The findings show that most people will settle into a cycle that is about 25 hours. Teens particularly tend to have a longer cycle, also, so they tend to go to bed later and later each night, and sleep later every morning. This is not just a bad habit for them. There is legitimate neuro-biology causing this problem. Unless they get some help overcoming their 25 hour cycle, disciplining their sleep, this can become a huge cause of sleep deprivation and difficulties in school.

            As we age, the opposite tends to happen, with a tendency to go to bed earlier and earlier in the evening. Since people in their sixth decade and beyond tend to need less than 8 hours of sleep a night, this leads to earlier and earlier awakening, and the perception that there is an insomnia problem. I have patients who complaint that they awaken at 3 AM and can’t get back to sleep, but upon questioning, they are going to bed at 8 PM, so they are getting 7 hours of sleep — probably all the sleep they need.

            Early awakening — the person who goes to sleep at 11 PM and awakens at 3 PM and can’t get back to sleep — is probably the most difficult of the sleep problems to overcome without pharmaceuticals, in my experience. Several things can contribute, however, that are easily fixed. One common cause of this, hypoglycemia, is overcome by changing eating habits.  A large carbohydrate load right before sleep can cause a person to wake up with anxiety about 2-3 hours later. It won’t feel like hunger, or your usual daytime hypoglycemia. It does feel like your body is awakening you with an alarm signal — which is exactly what’s happening. If getting up and eating helps you get back to sleep, consider this possibility. Stop eating carbs before dinner — have a high protein snack at least two hours or more before sleep time. A bit of yeast-free Glucose Tolerance Factor form of chromium could be helpful also.

            Worry and anxiety, chronic pain, and high levels of alcohol consumption also account for early morning awakening. There are breathing practices (abdominal breathing in one form or the other) that can help with anxiety, and also with pain. The hour of awakening can also be a clue to problems in certain organ systems. Various acupuncture meridians activate at specific hours on the 24 hour clock. For instance, I just went through a spell of awakening at 3 to 3:30 AM. That’s when the lung meridian activates, quite appropriate as I was getting over bronchitis at the time.

            Sleep onset is a more common problem. In chronic insomnia, this can even cause such a strong expectation of not sleeping,  that when these people go to bed they immediately begin to worry about not sleeping, which then keeps them from sleeping. Some sleep specialists advise purposefully depriving yourself of sleep to overcome this, by getting up very early in the morning, but going to bed the same time every night, to set your biological sleep cycle. Anti-anxiety natural substances, like valerian root and L-theanine (an extract from green tea) can help with this psychological part of sleep onset problems. L-theanine is also useful for awakening in the middle of the night. About 200 mg. of L-theanine at bedtime can help. An L-theanine spray is also available to help that squirrel-cage mind that can wake you up and keep you awake in the middle of the night. Dr. Vogt and I recently suggested that for a patient for whom we were having difficulty making a diagnosis of a fairly serious problem. He woke up with the mind running like crazy on all the ”what if’s”, sprayed the L-theanine under his tongue, and eventually slept. He told us he was fairly impressed, because that night “the squirrel was on steroids.”

            One of the body’s normal triggers for sleep, aside from the onset of darkness increasing output of melatonin, is the body begins to cool down. Core body temperature falls gradually for about 2 hours before we get sleepy. Therefore, though a nice hot bath may seem relaxing, if you warm up your body too much with extremely hot water, you will ruin this part of the body’s self-signaling for sleep.

            Since darkness is one of the triggers for sleep, you might assume that staring at a computer screen or too closely at a TV screen, presenting that kind of light stimulus to the eyes, might make for sleep delay. In fact, some rather recent studies have shown that is exactly correct.

            As we age, we manufacture  less of our own melatonin, so it makes sense to take some extra about an hour before bedtime. Don’t expect it to “put you to sleep” like a drug, however. Curiously, one of the most stunning recent findings in the treatment of autism is how helpful melatonin has been for many of these children. For children the dose is in the range of 1 mg. For adults, its about 3 mg. Taking amounts larger than 5 mg. at bedtime has no increased effectiveness.  So far, time seems to be proving this to be a safe supplement. The downside to melatonin is that its duration of action is quite short. While it may get you to sleep better, it won’t help if sleep maintenance is your problem. There are sustained release forms of melatonin on the market, now. There is also a drug (ramelteon) that attaches to the melatonin receptor which has a little longer duration of action than plain melatonin.

            There are many other herbs and supplements that help with relaxation and sleep. The health food stores are full of them. Here are just a few — chamomile, hops, valerian (which is also a good muscle relaxant), kava kava, tryptophan, 5-HTP, GABA, passion flower and catnip. My own experience with kava is interesting, and backed up by some information I later discovered. Kava relaxes the spinal cord part of the nervous system, but not the brain. When I tried to get some help from it, I laid awake just as long as ever, completely alert, but I didn’t care as much that I was not sleeping . Not everyone has this effect from it. I have since discovered that it is excellent for me if I have a talk to give, or some sort of challenging, anxiety producing stress. I am incredibly alert on kava, but very relaxed. Kava has received a bad rap for causing hepatitis, but the reported cases were in people who had taken large doses of kava for a long time. It may also be that the kava root is safer than leaves or stems.

            Valerian also receives a bad rap in some of the medical literature, all the ills and side effects of Valium being attributed to valerian. That’s because Valium was developed as a synthetic form of one of the components of valerian root. They are in no way the same thing. No one has ever been shown to be addicted to valerian, been able to commit suicide on valerian, nor does valerian cause dangerously deep sedation.

            Lavender, the essential oil, also has been studied. The smell of it is sedating and in fact it has been shown to help with insomnia. I will sometimes put just a dot of lavender oil on my pillow. This is helpful for both sleep onset and sleep maintenance forms of insomnia.

            After lying in bed for hours and not getting to sleep, most people get pretty antsy. The rule in good sleep hygiene is that you should get up. Read, do something relaxing, but get out of bed. Then, be sure you do not let yourself nap the next day.  I realize this is not possible for everyone. People with some fatigue disorders will not be able to manage without the nap, and some people are resting in bed even if not sleeping, who will feel worse if they get up when they cannot sleep. Use your own judgment. Lying in bed tense as a board and angry about not sleeping certainly is not restful. If you can switch your focus to prayer, meditation, a breathing practice, something relaxing and restful, then stay in bed. There is a thing called “sleep efficiency” which is how many hours you have to stay in bed to get 8 hours of sleep. During the height (or depth) of my own chronic fatigue syndrome, my sleep efficiency was horrible! It took about 12 hours in bed to get 6-7 hours of sleep. Curiously enough, chronic fatigue syndrome and fibromyalgia, while both involving deep levels of fatigue, also are associated with very poor sleep. Our brain actually has to flip a switch, so to speak, to sleep mode. It felt like my brain did not have the energy to flip the switch.

            Obviously, keep your bedroom dark, and quiet. Don’t have your desk with stacks of work on it in the bedroom. Feng shui would say don’t even have your treadmill in there. Find something very relaxing to do for at least a half hour before bedtime. Exercise helps, but not too close to bedtime. Remember, the body has to cool down for two hours. Avoid naps, avoid worry, avoid eating high carbohydrate snacks or for that matter eating much of anything right before bedtime. Get away from the computer, cell phone and TV for 30 minutes. If you read, for heaven’s sakes don’t read a spy novel or a murder mystery that you can’t put down.

            Obviously there are other sleep issues— post traumatic stress disorder, shift work, sleep apnea, restless leg syndrome, jet lag, and other major illness associated with loss of sleep — that I have not even tried to discuss here. It’s a huge topic, and one that retains some mystery despite all of science’s studies. Why, for instance, is dream sleep so essential to mental health? It is — even in animals. But why?

            Hope your dreams are pleasant ones.

Alice R. Laule, M.D.

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